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Updated: Aug 20, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Small lymphocytic lymphoma involving an enlarging complex renal cyst
Kenneth A Iczkowski1, Tracy B Gapin, Zev Wajsman
1Department of Pathology and Laboratory Medicine, Veterans Affairs Medical Center, Gainesville, FL 32608-1197, USA. iczkoka@pathology.ufl.edu
Abstract:
A 47-year-old white man presented for evaluation of a complex right renal mass. He had a history of human immunodeficiency virus. Cervical lymph node biopsy had revealed small lymphocytic lymphoma. Computed tomographic scan disclosed diffuse mesenteric and retroperitoneal adenopathy consistent with chronic lymphocytic leukemia, as well as a 4.5-cm complex cystic right renal mass, which 17 months later enlarged to 6.2 cm. The mass resembled multiloculated cystic nephroma. Partial nephrectomy revealed infiltration of the cyst wall by small lymphocytic lymphoma. To our knowledge, this is the first reported case of lymphoma arising in or colonizing a renal cyst.
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