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Updated: Aug 20, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Cefoxitin disk diffusion screen for confirmation of oxacillin-resistant Staphylococcus aureus isolates and utility in
Susan E Sharp1, Julie A Warren, Richard B Thomson
1Kaiser Permenente, Department of Pathology, Regional Laboratory, Portland, OR, USA. susan.e.sharp@kp.org
Abstract:
One hundred Vitek-2 identified oxacillin resistant S. aureus (ORSA) isolates were tested by oxacillin screen-plate (OXA-plate) and cefoxitin disk (FOX-disk) for confirmation of oxacillin resistance. Ninety-five of 100 confirmed oxacillin resistant by both, 3 of 5 were oxacillin susceptible by both and mecA negative, and 2 of 5 were oxacillin susceptible by OXA-plate, resistant by FOX-disk and mecA positive. The FOX-disk out-performed the OXA-plate for ORSA confirmation and can be performed using standard laboratory techniques.
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