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Synthesis of oxychelerythrine using lithiated toluamide-benzonitrile cycloaddition
1College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Kwangju, Korea.
Chemical & Pharmaceutical Bulletin
|January 7, 2005
Abstract:
Oxychelerythrine, benzo[c]phenanthridine alkaloid, was synthesized from easily available starting toluamide 5 and benzonitrile 6 using toluamide-benzonitrile cycloaddition reaction in 6 steps.
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