Haplotyping in biomedicine-practical challenges

A community-led initiative to de-risk and advance Parkinson's disease therapeutic targets.

NPJ Parkinson's disease·2025

Human genetic evidence enriched for side effects of approved drugs.

PLoS genetics·2025

Refining the impact of genetic evidence on clinical success.

Nature·2024

Future prospects for human genetics and genomics in drug discovery.

Current opinion in structural biology·2023

Using human genetics to improve safety assessment of therapeutics.

Nature reviews. Drug discovery·2022

Correction: High-resolution DNA size enrichment using a magnetic nano-platform and application in non-invasive prenatal testing.

The Analyst·2022

High numerical aperture confocal volumetric mesoscope reveals mesoscale subcellular dynamics in vivo.

Nature biotechnology·2026

High-fidelity fast fluorescence lifetime imaging by event-based denoising.

Nature biotechnology·2026

Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse.

Nature biotechnology·2026

High-resolution reconstruction of cell-type-specific transcriptional regulatory processes from bulk sequencing samples.

Nature biotechnology·2026

Efficient in vivo cytosine base editing using virus-like particles with uracil DNA glycosylase inhibition.

Nature biotechnology·2026

Engineered ADARs enable precision A-to-G base editing of DNA.

Nature biotechnology·2026

Purification of Advanced Therapeutics by Flow-Through Pseudo-Affinity Chromatography: Bi-Specific mABs, Fc Fusion Proteins, and Adeno-Associated Viruses.

Biotechnology and bioengineering·2026

Myelin Alteration in Neurodevelopmental Disorders: Integrating Clinical and Preclinical Evidence.

Current neuropharmacology·2026

Patient Communication Outside of Visits: Implications for Remote Monitoring and Digital Care Models in Myasthenia Gravis.

Muscle & nerve·2026

Enhanced transcriptional insulation of lentiviral vectors using "sequence-upgraded polyA long terminal repeats" or "supA-LTRs".

Molecular therapy. Advances·2026

Effect of Non-nucleoside Resistance-Associated Mutations on the Effectiveness of Long-Acting Cabotegravir + Rilpivirine Therapy: Insights From the Real-World RELATIVITY Cohort.

Open forum infectious diseases·2026

Chronic migraine management with onabotulinumtoxinA and anti-CGRP/R monoclonal antibodies in an Italian real-world setting: update on therapeutic appropriateness and an emerging role of pharmacy.

Frontiers in pharmacology·2026

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Haplotyping in biomedicine-practical challenges

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A community-led initiative to de-risk and advance Parkinson's disease therapeutic targets.

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Correction: High-resolution DNA size enrichment using a magnetic nano-platform and application in non-invasive prenatal testing.

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