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Multidisciplinary Approach to Obesity Management: A Case Report
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Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

[Characteristics of arterial hypertension in obesity]

Tatjana Ivković-Lazar1

  • 1Institut za interne bolesti, Klinika za endokrinologiju, dijabetes i bolesti metabolizma, Klinicki centar Novi Sad, Novi Sad.

Medicinski Pregled
|January 29, 2005
PubMed

Insights

Obesity-related arterial hypertension is linked to metabolic factors like insulin resistance. Treatment involves diet, exercise, and specific medications targeting these metabolic pathways.

Area of Science:

  • Cardiovascular Medicine
  • Metabolic Syndrome
  • Obesity Research

Context:

  • Arterial hypertension is highly prevalent in obese individuals.
  • Hypertension in obesity can lead to left ventricular hypertrophy, diastolic dysfunction, arrhythmias, and atherosclerosis.
  • Hemodynamic changes and metabolic factors, particularly insulin resistance and hyperinsulinism, are implicated in its pathogenesis.

Purpose:

  • To highlight the metabolic underpinnings of arterial hypertension in obesity.
  • To outline a treatment strategy informed by the metabolic basis of this condition.

Summary:

  • Arterial hypertension in obese individuals is frequently associated with cardiovascular complications.
  • Metabolic factors, especially insulin resistance and hyperinsulinism, are now considered primary drivers of hypertension in obesity, earning it the term 'metabolic hypertension'.
  • Treatment strategies emphasize lifestyle modifications (diet, reduced salt intake, physical activity) and pharmacotherapy including ACE inhibitors, alpha-1 blockers, and calcium channel blockers.

Impact:

  • Informed therapeutic approaches for metabolic hypertension in obesity.
  • Potential for improved cardiovascular outcomes in obese hypertensive patients.
  • Enhanced understanding of the link between metabolic health and cardiovascular disease.
Abstract

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