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[Whole gut irrigation in pediatric patients: a comparative study]
J J Vila Carbo1, C García-Sala, C Gutiérrez
1Departamento de Cirugía Pediátrica, Hospital Infantil La Fe, Valencia.
Summary
Digestive irrigation (D.I.) before surgery impacts pediatric patients
Area of Science:
- Surgical preparation
- Gastroenterology
- Pediatric surgery
Background:
- Digestive irrigation (D.I.) is used before surgery in pediatric patients.
- Observed changes in hydro-electrolytes, pH, and reduced infections prompted this study.
Purpose of the Study:
- Compare hydro-ionic and clinical effects of two D.I. solutions.
- Analyze D.I.'s impact on fecal flora and intestinal mucosa, with and without antibiotics.
Main Methods:
- Prospective, double-blind study.
- 124 pediatric patients received either saline (S-I) or Golytely (S-II) irrigation.
- Fecal flora and colonic mucosa were analyzed.
Main Results:
- Golytely (S-II) irrigation led to acidosis and dehydration.
- Saline irrigation (S-I) tended towards hyperhydration and alkalosis.
- D.I. significantly reduced colonic bacterial counts, especially anaerobes when antibiotics were added.
Conclusions:
- D.I. solutions have distinct hydro-ionic effects.
- Antibiotic-supplemented D.I. effectively reduces fecal flora.
- No histomorphologic changes in colonic mucosa were observed with erythromycin and neomycin base.