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Published on: August 7, 2017
Association between allergic rhinitis and hospital resource use among asthmatic children in Norway
V Sazonov Kocevar1, J Thomas, L Jonsson
1Merck and Co., Whitehouse Station, NJ 08889, USA.
Insights
Children with asthma and allergic rhinitis experience more hospitalizations and longer stays. This highlights the importance of managing allergic rhinitis in pediatric asthma patients to reduce healthcare resource use.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Health Services Research
Background:
- Inadequately controlled allergic rhinitis is linked to increased asthma exacerbations and poorer symptom control in asthmatic patients.
- This can lead to higher medical resource utilization.
- Understanding this association is crucial for effective asthma management.
Purpose of the Study:
- To assess the impact of co-occurring allergic rhinitis on asthma-related hospital resource utilization in children under 15 in Norway.
- To quantify the relationship between allergic rhinitis and hospital admissions and days among pediatric asthma patients.
Main Methods:
- Population-based retrospective cohort study using national hospital admission data (1998-1999).
- Included children aged 0-14 years with asthma.
- Multivariate regression models (linear and Cox proportional-hazards) analyzed associations with hospital days and readmission hazards, adjusting for covariates.
Main Results:
- Out of 2961 asthmatic children, 795 (26.8%) had a history of allergic rhinitis.
- Asthmatic children with allergic rhinitis showed a 1.72-times greater hazard of asthma-related readmissions.
- Concomitant allergic rhinitis predicted a significant increase in hospital days per year (0.23 days, P < 0.05).
Conclusions:
- Concomitant allergic rhinitis in asthmatic children is significantly associated with increased asthma-related hospital readmissions.
- The presence of allergic rhinitis also predicts a greater total number of hospital days.
- Integrated management of allergic rhinitis may reduce healthcare burden in pediatric asthma.
Background:
Preliminary evidence suggests that inadequately controlled allergic rhinitis in asthmatic patients can contribute towards increased asthma exacerbations and poorer symptom control, which may increase medical resource use. The objective of this study was therefore to assess the effect of concomitant allergic rhinitis on asthma-related hospital resource utilization among children below 15 years of age with asthma in Norway.
Methods:
A population-based retrospective cohort study of children (aged 0-14 years) with asthma was conducted using data from a patient-specific public national database of hospital admissions during a 2-year period, 1998-1999. Multivariate linear regression, adjusting for risk factors including age, gender, year of admission, urban/rural residence and severity of asthma episode, estimated the association between allergic rhinitis and total hospital days. A multivariate Cox proportional-hazards model estimated relative hazard of readmission according to concomitant allergic rhinitis status.
Results:
Among 2961 asthmatic children under 15 years of age with at least one asthma-related hospital admission over a 2-year period, 795 (26.8%) had a recorded history of allergic rhinitis. Asthmatic children with allergic rhinitis had a 1.72-times greater hazard of asthma-related readmissions than asthmatic children without allergic rhinitis. Multivariate analysis revealed that history of concomitant allergic rhinitis was a significant predictor of increased number of hospital days per year (least-squares mean difference 0.23 days, P < 0.05).
Conclusions:
Concomitant allergic rhinitis in asthmatic children was associated with increased likelihood of asthma-related hospital readmissions and greater total hospital days.
Related Concept Videos
Asthma-I: Introduction
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Asthma III: Clinical Manifestations

