Related Experiment Video
Updated: Aug 19, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Primary anorectal melanoma]
Fouad Haddad1, Salwa Nadir, Lamia Benkhaldoun
1Service d'hépato-gastro-entérologie, CHU Ibn Rochd, Casablanca, Maroc. haddadfouad@hotmail.com
Objective:
To specify the clinical and therapeutic aspects of anorectal melanoma.
Methods:
Nine cases of malignant anorectal melanoma were managed in the department of gastroenterology of the Ibn Rochd university hospital in Casablanca between 1984 and 2002.
Results:
There were 5 men and 4 women, with a mean age of 61 years. Clinical symptoms were dominated by rectal bleeding (7 cases) and rectal syndrome (5 cases). The tumor was blackish in 4 cases. Extension staging showed metastases in the liver in one patient and in the bones in another. One patient had undergone abdominoperineal resection, two transanal tumor resection, and in one patient radiotherapy was applied. Five patients refused any treatment. The outcome was marked by remission in 2 cases with an event free survival respectively of 10 and 21 months. Three patients died because of visceral metastases. Four patients were lost to follow-up.
Discussion:
The prognosis of anorectal melanoma is frightening because of late diagnosis and high malignancy potential. Treatment is based essentially on surgery.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...