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Updated: Jul 24, 2026

Cholesterol Efflux Assay
Published on: March 6, 2012
The enantiomer of cholesterol
1Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 S. Euclid, St. Louis, MO 63110, USA.
Abstract:
Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol)--which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol--is a unique tool that can be used to better understand the mechanisms of cholesterol function. We review the literature pertaining to ent-cholesterol, focusing in particular on its use in biological studies.
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