Related Experiment Video
Updated: Aug 11, 2026
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
[Study on the relationship of airborne sensitization fungus and anaphylactic rhinitis in Wuhan]
1Department of Allergy, Wuhan Rail Centre Hospital, Wuhan, 430064, China.
Objective:
The aim of our studies is to explore the relation between superior sensitizing fungus and anaphylactic rhinitis, for directing the prevention, diagnosis and treatment of the disease.
Method:
Three hundred and ninety-two persons were treated by allergen skin test. Using 15 main sensitizing fungus, 90 anaphylactic rhinitis were examined. The serum level of IgE were examined, too.
Result:
In the allergen skin testing 239 cases (60.97%) were positive, the positive rate was higher than that in contrast group (t = 5.47, P < 0.01). The main fungus allergen were Rhizopus nigricans, Cuvularia and Altevnaria, the value of IgE in patients group was higher than that in control group (t = 5.47, P < 0.01).
Conclusion:
It proves that airborne sensitizing fungus are important causes of anaphylactic rhinitis.
Insights
Airborne sensitizing fungi are significant causes of anaphylactic rhinitis. This study identified key fungal allergens and their link to elevated immunoglobulin E (IgE) levels in patients, aiding disease management.
Area of Science:
- Mycology
- Immunology
- Allergology
Context:
- Anaphylactic rhinitis is a common allergic respiratory condition.
- Identifying specific allergens is crucial for effective management.
- Fungal allergens are increasingly recognized as triggers for allergic diseases.
Purpose:
- To investigate the relationship between airborne sensitizing fungi and anaphylactic rhinitis.
- To identify prevalent fungal allergens responsible for allergic rhinitis.
- To assess immunoglobulin E (IgE) levels in patients with fungal-sensitized anaphylactic rhinitis.
Summary:
- Allergen skin testing on 392 individuals, including 90 with anaphylactic rhinitis, revealed a 60.97% positive rate for 15 main sensitizing fungi.
- Rhizopus nigricans, Curvularia, and Alternaria were identified as primary fungal allergens.
- Patients with anaphylactic rhinitis exhibited significantly higher serum IgE levels compared to the control group (t = 5.47, P < 0.01).
Impact:
- Establishes airborne fungi as important etiological agents in anaphylactic rhinitis.
- Provides data for targeted prevention and diagnosis strategies.
- Highlights the role of specific fungal allergens in disease pathogenesis and IgE elevation.
More Related Videos
09:02Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
Published on: September 22, 2023
06:08Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023