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Updated: Jul 29, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Clinical analysis on 18 cases of primary nasal cavity and sinuses T/NK lymphomas]
1Department of Otolaryngology, Huaxi Hospital, Sichuan University, Chengdu, 610041, China.
Objective:
To investigate the clinical characteristics and treatment effect of primary sinonasal T/NK lymphomas.
Method:
Eighteen cases of primary sinonasal T/NK lymphomas were reviewed retrospectively. The clinical behavior, clinical diagnostic characteristics and prognosis were studied.
Result:
The clinical symptoms of these patients included nasal obstruction, epistaxis, nasal discharge, intumescence, ulcer and fever so on. Clinical diagnosis was easy to be misdiagnosed. The prognosis of patients that higher stage and higher malignant were bad.
Conclusion:
Sinonasal T/NK lymphomas are a distinct clinicopathological category and the clinical symptoms are nonspecificness. We should pay attention to distinction and avoiding misdiagnosis. The prognosis is relative to pathological category and clinical stage.

