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An Ex Vivo Chicken Primary Bursal-cell Culture Model to Study Infectious Bursal Disease Virus Pathogenesis
Published on: October 4, 2018
Control of infectious bursal disease virus by vaccination
1Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA. saif.1@osu.edu
Abstract:
In summary, the currently used conventional vaccines are used effectively to control the disease. The promise of the new generation of vaccines has not materialized yet. This is partly due to the incomplete understanding of the molecular basis of immunogenicity resulting in an inadequate immune response. It should be emphasized that RNA viruses such as IBDV are prone to change through a variety of mechanisms. This requires vigilance in monitoring field viruses and the natural history of the disease.
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