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Acquired perforating disorder.

Olympia Kovich1

  • 1Ronald O. Perelman Department of Dermatology, New York University, USA.

Dermatology Online Journal
|March 8, 2005
PubMed
Summary
This summary is machine-generated.

Acquired perforating disorder (APD) presents as hyperkeratotic papules. This case highlights facial and upper extremity lesions, responding to topical tretinoin and intralesional glucocorticoids.

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Area of Science:

  • Dermatology
  • Keratinization Disorders

Background:

  • Acquired perforating disorder (APD) is a rare keratinization disorder.
  • It is frequently associated with systemic conditions like diabetes mellitus and uremia.
  • Classic APD typically manifests on the lower extremities.

Observation:

  • A 53-year-old male presented with asymptomatic facial and upper extremity lesions.
  • The lesions were characterized as hyperkeratotic papules and hyperpigmented macules.
  • This presentation deviates from the typical lower extremity predilection.

Findings:

  • The patient's condition involved unusual localization of acquired perforating disorder.
  • Treatment with topical tretinoin and intralesional glucocorticoids was initiated.
  • This suggests potential therapeutic efficacy for APD in atypical locations.

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Implications:

  • This case expands the understanding of APD's clinical presentation.
  • It underscores the importance of considering APD even with extralimbic involvement.
  • Further research into APD treatment protocols for varied presentations is warranted.