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[Brucellosis: 50 cases. Clinico-epidemiologic study and evaluation of diagnostic methods]
M I Grasa Lambea1, A Leoz Iparaguirre, A Gil Paraíso
1Servicio de Medicina Interna, Complejo Hospitalario San Millán-San Pedro, Logroño, La Rioja.
Anales De Medicina Interna (Madrid, Spain : 1984)
|February 1, 1992
Summary
This study on brucellosis found many cases had unknown transmission routes, particularly urban women. Early diagnosis is crucial due to long symptom periods before hospitalization.
Area of Science:
- Internal Medicine
- Infectious Diseases
- Epidemiology
Context:
- Retrospective analysis of 50 brucellosis cases from 1985-1990.
- High percentage of cases with unknown transmission mechanisms, especially in urban women.
- Brucellosis diagnosis often delayed due to oligosymptomatic presentation.
Purpose:
- To analyze brucellosis cases, identify risk factors, and evaluate diagnostic and treatment effectiveness.
- To highlight challenges in brucellosis transmission source identification.
- To assess the diagnostic utility of clinical observation, agglutination tests, and hemoculture.
Summary:
- Brucellosis diagnosis relies heavily on clinical signs and agglutination tests, with positive hemocultures in only 6% of cases.
- The average time from symptom onset to hospitalization and diagnosis was 48.6 days.
- Streptomycin and tetracycline remain effective treatments for brucellosis.
Impact:
- Emphasizes the need to investigate less common transmission sources and the survival of Brucella in various environments.
- Highlights the importance of considering non-pasteurized dairy products as a potential source.
- Underscores the need for improved diagnostic strategies and public health awareness regarding brucellosis transmission.