Related Experiment Video
Updated: Aug 19, 2026

Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
Probiotics: a complementary approach in the treatment and prevention of pediatric atopic disease
Neeta S Ogden1, Leonard Bielory
1Department of Allergy, Immunology and Rheumatology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07081, USA.
Insights
Probiotics show promise in preventing and managing pediatric atopic diseases by influencing the gut microbiota and immune response. Further research is ongoing to understand their long-term benefits.
Area of Science:
- Immunology
- Microbiology
- Pediatrics
Background:
- Atopic diseases in children are linked to altered immune responses.
- The gut microbiota plays a crucial role in immune system development and function.
Purpose of the Study:
- To review recent primary research on probiotics and pediatric atopic disease.
- To summarize developments in the past 10 years, focusing on literature since January 2003.
Main Methods:
- Literature review of primary research.
- Focus on studies published since January 2003.
Main Results:
- Probiotics are being investigated for primary prevention of atopic diseases.
- Probiotic use impacts cytokines in allergic immune responses.
- Long-term effects of perinatal probiotic administration are being studied.
- The gut microflora's relationship with atopic dermatitis is under investigation.
Conclusions:
- Probiotics are a key area of research for pediatric atopic diseases.
- Understanding the gut microbiota is vital for managing atopic conditions.
- Probiotics may serve as a complementary treatment for pediatric atopic diseases.
Purpose Of Review:
The goal of this article is to review recent primary research and developments in the area of probiotics and pediatric atopic disease.
Recent Findings:
Research developments in probiotics summarized in this article include the following: (1) the role of probiotics in primary prevention of atopic disease, (2) the effect of probiotics on cytokines involved in the allergic immune response, (3) the long-term effects of peri-natal probiotic use and (4) the relationship between the gut microflora and atopic dermatitis.
Summary:
Probiotics continue to be an area of active investigation as our understanding evolves of the gut microbiota's role in the altered immune response of atopic patients. Physicians should be aware of these developments as probiotics may be an important complementary approach in the treatment and the natural and long-term course of various pediatric diseases. This article summarizes the research conducted over the past 10 years with a primary focus on the literature published since January 2003.
Related Concept Videos
Probiotics
Microbiota Modulation by Antibiotics
Microorganisms in Medicine and Therapeutics
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Development of Human Microbiota
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...