Probiotics: a complementary approach in the treatment and prevention of pediatric atopic disease

Neeta S Ogden1, Leonard Bielory

  • 1Department of Allergy, Immunology and Rheumatology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07081, USA.

Insights

Probiotics show promise in preventing and managing pediatric atopic diseases by influencing the gut microbiota and immune response. Further research is ongoing to understand their long-term benefits.

Area of Science:

  • Immunology
  • Microbiology
  • Pediatrics

Background:

  • Atopic diseases in children are linked to altered immune responses.
  • The gut microbiota plays a crucial role in immune system development and function.

Purpose of the Study:

  • To review recent primary research on probiotics and pediatric atopic disease.
  • To summarize developments in the past 10 years, focusing on literature since January 2003.

Main Methods:

  • Literature review of primary research.
  • Focus on studies published since January 2003.

Main Results:

  • Probiotics are being investigated for primary prevention of atopic diseases.
  • Probiotic use impacts cytokines in allergic immune responses.
  • Long-term effects of perinatal probiotic administration are being studied.
  • The gut microflora's relationship with atopic dermatitis is under investigation.

Conclusions:

  • Probiotics are a key area of research for pediatric atopic diseases.
  • Understanding the gut microbiota is vital for managing atopic conditions.
  • Probiotics may serve as a complementary treatment for pediatric atopic diseases.
Abstract

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