Related Experiment Video
Updated: Aug 19, 2026
A Highly Reproducible and Straightforward Method to Perform In Vivo Ocular Enucleation in the Mouse after Eye Opening
Published on: October 6, 2014
"Finger-tip" cryoprobe assisted enucleation
1New York Eye Cancer Center, New York City 10021, USA. pfinger@eyecancer.com
Purpose:
To report the use of a new cryotherapy probe to induce proptosis during enucleation surgery.
Design:
Interventional case report.
Methods:
Two patients with uveal melanoma and secondary glaucoma were treated by enucleation. A large surface area (70 mm(2)), spatulated, end-freezing cryotherapy probe ("Finger-tip" probes, MIRA, Inc.) was used to induce proptosis during optic nerve transsection.
Results:
This new probe offers homogeneous freezing over a relatively large surface area. This new cryoprobe was used to create a large cryo-adhesion on the cornea, for an excellent purchase of the eye during enucleation surgery. Using this adhesion, the eye was lifted, enabling transsection of the optic nerve.
Conclusions:
This report includes photographs of the cryoprobe, the corneal cryo-adhesion, and describes its use for traction during enucleation surgery.
