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A Modified Method for Heterotopic Mouse Heart Transplantion
Published on: June 23, 2014
Selection of congestive heart failure patients for heart transplant
Pedro Ortiz Lamas1, José O García Burgos, Rafael Calderón
1Department of Medicine, Section of Cardiology, University of Puerto Rico, San Juan, Puerto Rico.
Insights
Heart transplant is a viable treatment for advanced heart failure. This review guides physicians on patient selection, workup, and management for cardiac transplant candidates.
Area of Science:
- Cardiology
- Transplantation Medicine
Background:
- Heart failure is a leading cause of adult hospitalization.
- Heart transplantation is an established therapy for select advanced heart failure patients.
Purpose of the Study:
- To guide physicians on the evaluation and management of cardiac transplant candidates.
- To detail indications, contraindications, and pre-transplant optimization.
Main Methods:
- Review of current practices and literature for cardiac transplantation.
- Focus on clinical and psychosocial assessment.
- Emphasis on medical therapy optimization.
Main Results:
- Defines eligibility criteria for heart transplantation.
- Outlines necessary pre-transplant workup procedures.
- Highlights absolute and relative contraindications.
Conclusions:
- Cardiac transplantation offers a definitive solution for carefully selected patients with advanced heart failure.
- Physician familiarity with transplant protocols is crucial for successful patient outcomes.
Abstract:
Heart failure is one of the most common causes of hospitalization in adult patients. With the recent technological advances and the use of new medications for controlling rejection, heart transplant has been established as a definite therapeutic measure for properly selected patients with advanced congestive heart failure. As there is an active transplant program in the Cardiovascular Center of Puerto Rico and the Caribbean, this review is intended to acquaint the practicing physician with the required work up and management of patients referred for cardiac transplant. Emphasis is given to indications, clinical and psychosocial evaluation, optimization of medical therapy and to the absolute and relative contraindications.
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