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Related Experiment Videos

Tinea capitis: a treatment update.

Brandie J Roberts1, Sheila Fallon Friedlander

  • 1Children's Hospital and Health Center and University of California San Diego Medical Center, San Diego, CA, USA.

Pediatric Annals
|March 29, 2005
PubMed
Summary
This summary is machine-generated.

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Griseofulvin is the standard treatment for tinea capitis, but newer antifungals like terbinafine show comparable efficacy and safety. Antifungal shampoos can help reduce spore viability and transmission.

Area of Science:

  • Dermatology
  • Mycology
  • Pharmacology

Background:

  • Griseofulvin is the FDA-approved, first-line treatment for tinea capitis.
  • It possesses high efficacy and a favorable long-term safety profile.
  • Alternative antifungal agents are increasingly recognized for treating this condition.

Purpose of the Study:

  • To review the efficacy and safety of alternative antifungal agents for tinea capitis.
  • To compare these agents with griseofulvin.
  • To inform clinical practice regarding treatment options.

Main Methods:

  • Review of existing studies on terbinafine, itraconazole, and fluconazole for tinea capitis.
  • Comparison of efficacy and safety data against griseofulvin.
  • Summary of therapeutic guidelines for alternative agents.

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Main Results:

  • Terbinafine, itraconazole, and fluconazole demonstrate comparable efficacy and safety to griseofulvin in short-term use.
  • These agents are often used off-label for patients who fail or react to griseofulvin.
  • Ongoing trials may influence future standard of care for tinea capitis treatment.

Conclusions:

  • While griseofulvin remains first-line, alternative antifungals offer viable options for tinea capitis.
  • Patients and families must be informed about the off-label use of terbinafine, itraconazole, and fluconazole.
  • Adjuvant antifungal shampoos are recommended for all patients and contacts to minimize spore transmission.