Related Experiment Video
Updated: Aug 18, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Mitral valve replacement in a patient with severe thrombophilic status and direct antiglobulin test positivity: case
Stefano Mastrobuoni1, Giuseppe Avvisati, Maria Cristina Tirindelli
1Interdisciplinary Center for Biomedical Research (CIR), Università Campus Bio-Medico, Rome, Italy. S.Mastrobuoni@unicampus.it
Abstract:
The case is reported of a patient with a symptomatic thrombophilic status and a positivity for both direct and indirect antiglobulin tests who underwent mitral valve replacement. Because of the antiglobulin test positivity, the patient was enrolled in a preoperative autologous blood donation program in order to avoid exposure to allogenic blood. The operation was successful, and the postoperative course uneventful; the patient was discharged on postoperative day 6 and prescribed oral anticoagulation. This case suggests that a safe valve replacement can be carried out even in the presence of a symptomatic thrombophilic preoperative status.
Related Concept Videos
Mitral Stenosis III: Medical Management
Mitral Regurgitation III: Medical Management
Venous Thrombosis III: Interprofessional Care
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Valve Prolapse II: Assessment and Management
Mitral Stenosis II: Clinical features and Diagnostic Tests