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Surgical site infections after pediatric intracranial surgery for craniofacial malformations: frequency and risk
Laurence C Yeung1, Michael L Cunningham, Amanda L Allpress
1School of Medicine, University of Washington, Seattle, Washington, USA.
Insights
Surgical site infections (SSIs) are a concern in pediatric intracranial surgery for craniofacial malformations. Complicated diagnoses and longer surgeries increase SSI risk, highlighting the need for targeted prevention strategies.
Area of Science:
- Pediatric Surgery
- Infectious Diseases
- Craniofacial Surgery
Background:
- Surgical site infections (SSIs) are common and serious complications following pediatric intracranial surgery for craniofacial malformations.
- Limited research exists on the incidence and risk factors for SSIs in this specific patient population.
Purpose of the Study:
- To determine the incidence of SSIs after pediatric intracranial surgery for craniofacial malformations.
- To identify factors associated with the development of SSIs in this patient group.
Main Methods:
- A retrospective chart review of 254 patients undergoing 281 intracranial procedures over a 6-year period.
- Comparison of patients with SSIs (cases) to those without SSIs (controls) using National Nosocomial Infection Surveillance System criteria.
Main Results:
- The incidence of SSIs was 3.2% (9 out of 281 procedures).
- Factors associated with SSIs included complicated diagnoses (e.g., syndromic craniosynostosis), prolonged surgery (>426 minutes), skin closure under tension, multiple surgeons (>4), extended pediatric intensive care unit stay (>2 days), and post-operative ventilator use.
Conclusions:
- Complicated diagnoses and several surgical and post-operative factors are significantly associated with SSIs in pediatric craniofacial surgery.
- These factors may serve as markers for increased SSI risk, warranting consideration in future research and clinical practice.
Objective:
Surgical site infections (SSIs) after pediatric intracranial surgery for craniofacial malformations are relatively common and potentially serious nosocomial infections. Despite this, few studies have been published on this topic. We performed a retrospective study to determine the incidence of and factors associated with SSIs after intracranial surgery for craniofacial malformations at a single multidisciplinary craniofacial center during a 6-year period.
Methods:
Retrospective chart review was performed on 254 patients who underwent 281 intracranial procedures during a 6-year period. Patients with SSIs (cases) were compared with those without SSIs (controls). National Nosocomial Infection Surveillance System criteria were used to identify cases of SSI.
Results:
SSIs occurred in 9 (3.2%) of 281 intracranial procedures that took place during the study period. Factors associated with an SSI included a complicated diagnosis comprising a diagnosis of syndromic craniosynostosis, frontonasal dysplasia, or oblique facial cleft (odds ratio [OR], 13.0; 95% confidence interval [CI], 2.6-64.4); duration of surgery longer than 426 minutes (OR, 12.1; 95% CI, 2.4-59.9); closure of skin under tension (OR, 12.5; 95% CI, 3.0-52.6); use of bovine pericardium (OR and 95% CI undefined); more than four surgeons present during surgery (OR, 6.3; 95% CI, 1.2-32); pediatric intensive care unit stay longer than 2 days (OR, 10.8; 95% CI, 2.2-53.3); and use of a ventilator after surgery (OR, 4.8; 95% CI, 1.2-18.6).
Conclusion:
In this study, the presence of a complicated diagnosis and a number of other factors were associated with an SSI after pediatric intracranial surgery for craniofacial malformations. We speculate that a complicated diagnosis may be a marker for other factors that contribute to the risk of an SSI. Future studies investigating SSIs after intracranial surgery should consider these factors.
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