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[Cutaneous-mucosal paracoccidio-domycosis: the first case diagnosed in French Guiana]
F Sarazin1, D Sainte-Marie, M Demar
1Service de Dermatologie, Centre Hospitalier, Cayenne, Guyane Française.
Annales De Dermatologie Et De Venereologie
|March 31, 2005
Summary
Paracoccidioidomycosis, a fungal infection, was diagnosed in French Guiana for the first time. This case highlights the importance of considering imported fungal diseases in endemic areas.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Paracoccidioidomycosis is a deep mycosis caused by the dimorphic fungus *Paracoccidioides brasiliensis*.
- Brazil is the primary endemic country for this infection.
- This report details the first diagnosis of paracoccidioidomycosis in its cutaneous-mucosal form in French Guiana.
Observation:
- A 20-year-old Brazilian man, recently relocated to French Guiana, presented with disseminated cutaneous lesions and mucosal ulcerations.
- Clinical examination revealed facial nodules, ulcerations, and enlarged superficial lymph nodes.
- Biopsies confirmed the presence of *Paracoccidioides brasiliensis*.
Findings:
- Direct examination, anatomopathology, and culture of cutaneous biopsies confirmed *Paracoccidioidomycosis*.
- The patient had negative HIV serology.
- Treatment with cotrimoxazole and itraconazole resulted in lesion resolution within one month.
Implications:
- This case likely represents an imported instance of paracoccidioidomycosis.
- Leishmaniasis was considered a primary differential diagnosis.
- This diagnosis underscores the need for awareness of deep mycoses in non-endemic regions, especially in travelers from endemic areas.