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Updated: Aug 18, 2026
Murine Model of Epicutaneously-Induced Immunomodulation
Published on: June 24, 2025
[Effects of exopolysaccharide from Tolypocladium sinense on murine immunocytes in vitro]
Jinyu Yang1, Weiyun Zhang, Peihua Shi
1Medical School, Nanjing University, Nanjing.
Objective:
To elucidate the effects of exopolysaccharide from Tolypocladium sinense on murine immunocytes in vitro.
Methods:
Extracted exopolysccharide (EPS) from cultured Tolypocladium sinense. The effects of EPS on mouse immune parameters were detected in vitro using cell culture techniques.
Results:
The results indicated that EPS might significantly not only promote mouse macrophage neutral red uptake ability and cytotoxicity (P < 0.05), but also stimulate their thymus lymphocytes proliferation (P < 0.05).
Conclusion:
EPS may elevate murine cellular immunity to a certain.
