Related Experiment Video
Updated: Aug 18, 2026

Eye Movement Monitoring of Memory
Published on: August 15, 2010
Directing the mind's eye: prefrontal, inferior and medial temporal mechanisms for visual working memory
Charan Ranganath1, Mark D'Esposito
1Center for Neuroscience and Department of Psychology, University of California at Davis, 1544 Newton Ct., Davis, CA 95616, USA. cranganath@ucdavis.edu
Abstract:
Human and nonhuman primates have a remarkable ability to recall, maintain and manipulate visual images in the absence of external sensory stimulation. Evidence from lesion, single-unit neurophysiological and neuroimaging studies shows that these visual working memory processes are consistently associated with sustained activity in object-selective inferior temporal neurons. Furthermore, results from these studies suggest that mnemonic activity in the inferior temporal cortex is, in turn, supported by top-down inputs from multimodal regions in prefrontal and medial temporal cortex, and under some circumstances, from the hippocampus.
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