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Updated: Aug 18, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
[Comparative evaluation of different infusion medias used in therapy for neonatal hypovolemia]
Abstract:
The paper comparatively evaluates the efficiency of the use of physiological sodium chloride solution, freshly-frozen plasma, 6% and 10% solutions of hydroxyethyl starch to compensate for circulating blood volume deficit in 80 neonatal infants aged 1-3 days who had hypovolemia resulting from hemorrhage during labor or abdominal delivery. 6% and 10% solutions of hydroxyethyl starch were found to be the most effective agents for compensating for circulating plasma volume deficit. They rapidly eliminate circulating blood volume deficit, long maintain the stability of systemic and peripheral hemodynamic parameters.
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