[Efferent potential-dependent ionic currents developing in frog myoblast culture]
Abstract:
Variety of outward voltage-dependent currents in cultured frog myoblasts were registered by means of whole cell voltage clamp. Six types of potassium currents (Ik) which reach the peak value (-10 mV) in 5, 12, 20, 30, 50 ms (fast) and do not reach the maximum in 7 s (slow) were established. High sensitivity to low temperature (+5 degrees) was shown for channels of very fast and of slow non-inactivated Ik. The assumption is made that some of Ik--5, 20 and 30 ms to peak are especially characteristic of myoblasts fusion stage.
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Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
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Resting Phase:
In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...


