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Updated: Aug 18, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Reported practices of antimicrobial use for upper respiratory tract infections]
Lutfi Jaber1, Orly Aromano-Zelekha, Shmuel Rigler
1The Bridge to Peace Community Pediatric Center, Taibe, Israel. jabe@bezeqint.net
Aim:
To determine the reported antibiotic prescribing practices for upper respiratory tract infections in children among pediatricians and family physicians.
Methods:
Regional survey of practicing pediatricians and family physicians and comparison of the survey responses of 81 physicians with the recently published recommendations of the Centers for Disease Control and Prevention.
Results:
Whereas almost all the physicians agreed that a diagnosis of acute otitis media required documentation of middle ear effusion and acute illness, 28% of family physicians and 12% of pediatricians reported that they routinely prescribed antibiotics for children with bronchitis, even though this is not recommended. In this survey 39% of pediatricians and 47% of family physicians reported that they omitted laboratory testing for the diagnosis of group A streptococcal pharyngitis, and of those who submitted samples for testing, most reported that they prescribed antibiotics immediately without waiting for the results. Even though these recommendations state that sinus tenderness is rare in young children with sinusitis, more than 48% of the physicians believed that both this and the presence of purulent rhinitis were essential to confirm this diagnosis. While none of the pediatricians reported prescribing antibiotics for the common cold, 17% of the family physicians did so (p = 0.006).
Conclusions:
The reported prescribing practices of the physicians in this survey are not in line with the recommendations. Effective intervention is needed to encourage the judicious use of antibiotics in Israel.
Insights
Physician antibiotic prescribing for pediatric respiratory infections deviates from guidelines. Interventions are needed to promote appropriate antibiotic use in Israel.
Area of Science:
- Pediatric infectious diseases
- Antimicrobial stewardship
- General practice
Context:
- Antibiotic resistance is a growing global health concern.
- Guidelines exist for appropriate antibiotic prescribing in children.
- Physician prescribing habits may not align with current evidence-based recommendations.
Purpose:
- To assess pediatrician and family physician antibiotic prescribing practices for pediatric upper respiratory tract infections (URTIs).
- To compare reported practices with Centers for Disease Control and Prevention (CDC) guidelines.
Summary:
- A survey of 81 physicians revealed significant discrepancies between reported practices and recommendations.
- Common issues included prescribing antibiotics for bronchitis and the common cold, and not adhering to diagnostic criteria for pharyngitis and sinusitis.
- Many physicians initiated antibiotics before test results were available.
Impact:
- Physician prescribing patterns for pediatric URTIs in Israel are not fully aligned with established guidelines.
- There is a need for targeted interventions to improve judicious antibiotic prescribing among healthcare providers.
- Optimizing antibiotic use can help combat antimicrobial resistance and improve patient outcomes.
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