Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional connectivity during working memory maintenance.

Adam Gazzaley1, Jesse Rissman, Mark D'Esposito

  • 1University of California, Berkeley, California 94720, USA. adamgazz@comewander.com

Cognitive, Affective & Behavioral Neuroscience
|April 27, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic Circuits.

Human brain mapping·2026
Same author

Functional brain organization is stable within individuals across years.

bioRxiv : the preprint server for biology·2026
Same author

Predicting Substance Use and Psychotic-Like Experiences in Adolescents.

medRxiv : the preprint server for health sciences·2026
Same author

Behavioural separation of face memory and face perception.

Nature communications·2026
Same author

Alpha phase coding supports feature binding during working memory maintenance.

Communications biology·2026
Same author

Measuring and increasing the brain health span across adulthood: a public health imperative.

Scientific reports·2026
Same journal

The role of sleep in strengthening face learning and memory consolidation: A systematic review.

Cognitive, affective & behavioral neuroscience·2026
Same journal

How the brain represents a romantic partner: Dissociable roles of the nucleus accumbens and anterior insula.

Cognitive, affective & behavioral neuroscience·2026
Same journal

Predictive processing in time perception: Assessing prediction error minimization in the sub-second range.

Cognitive, affective & behavioral neuroscience·2026
Same journal

When attention falters: Brain, breathing, and behavioral signals of lapses in interoceptive attention.

Cognitive, affective & behavioral neuroscience·2026
Same journal

Fronto-Parietal EEG asymmetry interactions predict negative attention bias: A secondary data analysis.

Cognitive, affective & behavioral neuroscience·2026
Same journal

Correction: The neural basis of cost-benefit trade-offs in effort investment: a quantitative activation likelihood estimation meta-analysis.

Cognitive, affective & behavioral neuroscience·2026
See all related articles

This study reveals how the brain actively maintains visual information using a network of interacting regions. Functional connectivity analysis shows coordinated activity between the fusiform face area and other brain areas during working memory tasks.

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Cognitive Psychology

Background:

  • Working memory (WM) relies on persistent neural activity in regions like the prefrontal cortex (PFC).
  • Interactions between distant brain regions are crucial for WM but difficult to study with traditional methods.
  • Previous research provides indirect evidence for regional integration during WM maintenance.

Purpose of the Study:

  • To explore functional connectivity between brain regions during distinct stages of a delayed face recognition task.
  • To characterize the neural network mediating on-line maintenance of faces during working memory.
  • To investigate the coordinated interaction of brain regions underlying perceptual representation maintenance.

Main Methods:

  • Utilized a novel multivariate analysis method to assess functional connectivity.

Related Experiment Videos

  • Defined the fusiform face area (FFA) as a seed region for whole-brain correlation mapping.
  • Employed a delayed face recognition task to examine neural activity during WM maintenance.

    • Main Results:

    • A network of brain regions showed significant correlations with the FFA during the WM delay period.
    • This maintenance network included the dorsolateral and ventrolateral PFC, premotor cortex, and intraparietal sulcus.
    • The network also encompassed the caudate nucleus, thalamus, hippocampus, and occipitotemporal regions.

    Conclusions:

    • Findings support the concept of a widely distributed neural network for active perceptual representation maintenance.
    • Coordinated functional interactions between network nodes are essential for working memory.
    • This study provides direct evidence for regional integration in visual working memory.