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Published on: October 17, 2025
[T-cell acute lymphoblastic leukemia /orbital lymphoblastic lymphoma in children]
K Abdelouahed1, M Laghmari, S Tachfouti
1Service Ophtalmologie A, Rabat, Maroc.
Insights
A rare pediatric case of T-cell lymphoblastic lymphoma presenting as orbital proptosis was diagnosed and treated. The patient achieved complete remission, highlighting successful management of this rare condition.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Hematology
Background:
- Orbital tumors in children are rare and pose diagnostic challenges.
- T-cell lymphoblastic lymphoma is an uncommon malignancy, particularly in the orbit.
Observation:
- A 6-year-old pediatric patient presented with acute proptosis of the right eye following trauma.
- CT scan revealed a mass involving the orbit, maxillary sinus, and zygoma with intracranial extension.
Findings:
- Histopathology confirmed T-cell lymphoblastic lymphoma.
- Systemic evaluation revealed concomitant acute lymphoblastic leukemia.
- The patient achieved complete remission after 13 months on the LMT96 Protocol.
Implications:
- This case underscores the importance of thorough investigation for rare orbital malignancies in children.
- Successful treatment demonstrates the efficacy of established protocols even in complex pediatric cases.
- Highlights the diagnostic challenges and rarity of primary orbital T-cell lymphoblastic lymphoma in pediatric patients.
Case:
The authors report a case of an 6-year-old pediatric patient with a history of acute onset of proptosis of his right eye. He was admitted at hospital 6 months ago for proptosis concomitant with orbital trauma. Computed tomography scan demonstrated a mass involving the right orbit, right maxillary sinus, and zygoma with endocranial extension.
Results:
Incisional biopsy of the mass revealed after of histopathologic and immuno-histochemical evaluation a T-cell lymphoblastic lymphoma. Systemic examination and bone marrow aspirate show a acute lymphoblastic leukemia. The patient was treated with LMT96 Protocol. A complete Remission was observed after 13 months of follow up.
Conclusion:
Primary T-cell lymphoblastic lymphoma of the orbit is a rare entity in any age group, but it is very rare in children. When tumors occurs in the orbit, it presents a challenging diagnosis problem, especially in pediatric patients.
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