Simultaneous carotid and coronary arteries disease: staged or combined surgical approach?

Patients suffering from a concomitant coronary and carotid artery occlusive disease represent a high-risk population whose management remains controversial.

Between April 1979 and June 2002, 202 patients (163 men and 39 women, mean age 65 +/- 7 years) were admitted at the Department of Cardiovascular Surgery of the University of Bologna for coronary artery bypass graft and carotid endarterectomy (CEA). In Group 1 (140 patients) coronary artery bypass graft and carotid endarterectomy were performed simultaneously while in Group 2 (62 patients) they were performed as two-staged procedures.

The rate of postoperative stroke was 6.4% in Group 1 (9/140) and 4.8% in Group 2 (3/62). Significant univariate predictors of myocardial infarction were smoking history and previous myocardial infarction; for stroke they were older, greater than 70 years, and a smoking history; for death the significant predictors were the operative approach, the low ejection fraction, smoking history, renal failure, and peripheral vascular occlusive disease. The hospital mortality was 6.4% in Group 1 versus 12.9% in Group 2.

Despite the highly selected populations, the contemporary surgical results indicate that the management of these patients needs careful pre-, intra-, and postoperative assessment and timing aimed at reducing the ischemic injuries, both cerebral and cardiac, therefore we believe that the surgical technique should be individualized for each patient.