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[Expression of SSX2 gene in human urologic neoplasms]
Peng Du1, Li-zhang Yu, Ming Ma
1Department of Urology, The First Hospital of Peking University, Institute of Urology, Peking University, Beijing 100034, China. lihanDP@yahoo.com.cn
Objective:
To investigate the expression of SSX(2)gene in human renal cell carcinoma and urinary transitional cell carcinoma.
Methods:
Reverse-transcription polymerase chain reaction (RT-PCR) was used for detecting SSX(2) gene in the specimens from renal cell carcinoma (n = 26), urinary transitional cell carcinoma (n = 27) and in 15 specimens taken from the tumor surrounding tissues.
Results:
Positive expression of SSX(2) gene at mRNA was detected in 69% renal cell carcinomas (18/26), in 81% urinary transitional cell carcinomas (22/27). The mRNA of SSX(2) was not detected in the 15 specimens from tumor surrounding tissues.
Conclusion:
The SSX(2) gene is highly expressed in human renal cell carcinoma and urinary transitional cell carcinoma.
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