Related Experiment Video
Updated: Aug 18, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Factor V Leiden and its effect on children with cardiac pathology
1Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. Jean.Connor@cardio.chboston.org
Abstract:
Factor V Leiden thrombophilia, formed by a genetic mutation, slows the body's anticoagulation response to clot formation. First described in 1994, factor V Leiden mutation has been identified as a contributing risk factor for venous thromboembolism. Although venous thromboembolism is considered rare in the pediatric population, Factor V Leiden has implications for certain at-risk pediatric patients.
Related Concept Videos
Cardiac Catheterization III: Left Heart Catheterization
Mitral Stenosis III: Medical Management
Venous Thrombosis I: Introduction
