Related Experiment Video
Updated: Aug 18, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
Published on: May 31, 2024
Long-term functional results after straight or colonic J-pouch coloanal anastomosis
Guillaume Portier1, Ivan Platonoff, Frank Lazorthes
1Service de Chirurgie Digestive, CHU Purpan, Place du Dr. Baylac, 31059 Toulouse, France. portier.g@chu-toulouse.fr
Abstract:
Proctectomy followed by straight coloanal anastomosis (CAA) often results in poor functional outcome known as the anterior resection syndrome. It is now based on evidence that a colonic J-pouch CAA improves outcome in the first 2 years. We assessed the very late functional outcome of CAA patients with or without a pouch. These results show that the functional benefit of the J-pouch anastomoses is sustained over the very long term.
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