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A new initiative in nephrology: 'Kidney disease: improving global outcomes'
Norbert Lameire1, Garabed Eknoyan, Rashad Barsoum
1University Hospital of Ghent, Ghent, Belgium.
Insights
Chronic kidney disease (CKD) is a growing global health issue. Early detection and evidence-based care can slow progression and reduce adverse outcomes, necessitating a unified global public health strategy.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Background:
- Chronic kidney disease (CKD) represents a significant global health burden with increasing incidence and prevalence.
- A higher prevalence of earlier-stage CKD exists, associated with adverse outcomes including kidney failure, cardiovascular disease, and premature mortality.
- Early detection via laboratory testing and effective treatments can mitigate CKD progression and cardiovascular events.
Purpose of the Study:
- To address the worldwide epidemic of CKD by advocating for a uniform and global public health approach.
- To introduce the 'Kidney Disease: Improving Global Outcomes' initiative.
- To outline current and future activities of the initiative, including guideline development and resource creation.
Main Methods:
- Review of the global burden and outcomes of chronic kidney disease.
- Description of the establishment and objectives of the 'Kidney Disease: Improving Global Outcomes' initiative.
- Outline of planned activities such as classification modification, guideline development, consensus conferences, and comparative website creation.
Main Results:
- Identified the need for a unified global public health strategy for CKD.
- Established the 'Kidney Disease: Improving Global Outcomes' initiative to address this need.
- Proposed specific activities including guideline development and comparative resources for clinical practice.
Conclusions:
- A global, evidence-based approach to CKD care is essential and universally applicable.
- The 'Kidney Disease: Improving Global Outcomes' initiative aims to standardize and improve CKD management worldwide.
- Future activities will focus on refining CKD classification, developing guidelines, and providing accessible comparative resources for clinicians.
Abstract:
The burden of kidney disease: Improving global outcomes. Chronic kidney disease (CKD) is a worldwide public health problem with an increasing incidence and prevalence of patients requiring replacement therapy. There is an even higher prevalence of patients in earlier stages of CKD, with adverse outcomes such as kidney failure, cardiovascular disease, and premature death. Patients at earlier stages of CKD can be detected through laboratory testing and their treatment is effective in slowing the progression to kidney failure and reducing cardiovascular events. The evidence-based care of these patients are universal and independent of their geographic location. This paper describes the need to develop a uniform and global public health approach to the worldwide epidemic of CKD. It is to this end that a new initiative Kidney Disease: Improving Global Outcomes' has been established. Some current and future activities of this initiative are described. They include among others modification of the classification of CKD, the development of guidelines on hepatitis C, the organisation of consensus conferences like on Renal Osteodystrophy, and the creation of a website allowing the comparison of the five main English language clinical practice guidelines in kidney disease worldwide.
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