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Urticaria and angioedema.

Sachin Baxi¹, Chitra Dinakar

¹Division of Allergy/Asthma/Immunology, University of Missouri-Kansas City, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA.

Immunology and Allergy Clinics of North America

|May 10, 2005

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Pediatric urticaria and angioedema diagnoses are clear, but chronic cases often have autoimmune causes. Management involves trigger avoidance, medications, and reassurance for effective control.

Area of Science:

Pediatric Allergy and Immunology
Dermatology
Immunology

Background:

Urticaria and angioedema are frequent pediatric complaints.
Identifying the cause of chronic urticaria can be difficult.
Autoimmune factors are increasingly recognized in chronic urticarial cases.

Purpose of the Study:

To review recent advancements in understanding urticaria and angioedema in children.
To discuss the pathogenesis, diagnostic testing, and therapeutic options for these conditions.

Main Methods:

Literature review of current research on urticaria and angioedema.
Synthesis of information on diagnostic approaches and treatment strategies.

Main Results:

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Progress has been made in understanding the autoimmune basis of chronic urticaria.

Established diagnostic pathways and a range of medications are available.

Effective management strategies exist for most pediatric cases.

Conclusions:

While diagnosis is straightforward, determining the etiology of chronic urticaria requires careful evaluation.
Autoimmunity plays a significant role in a substantial number of chronic urticaria cases.
Comprehensive management, including trigger avoidance and pharmacotherapy, typically controls symptoms effectively.