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Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
Published on: January 17, 2014
Head and neck infections caused by Streptococcus milleri group: an analysis of 17 cases
Tomohisa Hirai1, Shinji Kimura, Naoki Mori
1Department of Otorhinolaryngology, Head and neck surgery, Hiroshima Prefectural Hospital, 1-5-54 Ujinakanda, Hiroshima 734-8530, Japan. t-hirai@hph.pref.hiroshima.com
Background:
Streptococcus milleri group (SMG) is a common inhabitant of the mouth and gastrointestinal tract, and can be an aggressive pathogen causing abscess formation at various sites in the body. However, it has rarely been listed as a cause of head and neck infections.
Objectives:
The present study was performed to evaluate the clinical significance of SMG by reviewing the microbiology and clinical records of patients with SMG in head and neck infections retrospectively.
Study Design:
A retrospective review of all patients diagnosed as having SMG bacterial infections at Onomichi General Hospital, Hiroshima, between the years 2001 and 2002 was performed; 17 patients developed head and neck infections with SMG. Here, we describe the clinical features and management of SMG in head and neck infection.
Results:
The patient population consisted of 12 males and 5 females with a median age of 62 years (age range, 8-78 years). The sites of infection were as follows: maxillary sinus (n=6), peritonsillar region (n=4), subcutaneous (n=3), submandibular space-retropharyngeal space (n=1), deep neck-mediastinum (n=1), parapharyngeal space (n=1), submandibular space (n=1), tonsil (n=1), parotid gland (n=1), and masseter muscle (n=1). Ten cases (59%) were of suppurative diseases. Six cases (35%) had mixed SMG with anaerobe infection. Three cases showed deteriorating clinical courses, and all three of these cases were culture-positive for SMG with anaerobes. In addition, one deteriorating case showed gas gangrene regardless of repeated surgical debridement and intravenous antibiotic therapy; hyperbaric oxygen therapy improved this patient's condition.
Conclusion:
It is important to recognize SMG as a pathogen in head and neck infection. In addition, the care should be taken with infectious diseases caused by SMG with anaerobes as the patient's clinical course can deteriorate rapidly.
Insights
Streptococcus milleri group (SMG) can cause serious head and neck infections, especially when combined with anaerobic bacteria. Prompt recognition and treatment are crucial for managing these aggressive infections.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Microbiology
Background:
- Streptococcus milleri group (SMG) bacteria are common in the oral and GI tracts.
- While typically commensal, SMG can cause abscesses but is rarely implicated in head and neck infections.
Observation:
- A retrospective study reviewed 17 head and neck infection cases caused by SMG between 2001-2002.
- Infections occurred in various head and neck sites, including the maxillary sinus and peritonsillar region.
- 59% of cases were suppurative, and 35% involved mixed SMG and anaerobic infections.
Findings:
- Three patients with mixed SMG and anaerobic infections experienced rapidly deteriorating clinical courses.
- One patient developed gas gangrene, which improved with hyperbaric oxygen therapy.
Implications:
- SMG should be recognized as a significant pathogen in head and neck infections.
- Co-infections with anaerobic bacteria require careful management due to potential for rapid clinical decline.
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