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Updated: Jul 8, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
Chiral discrimination in photochromic helicenes
Tony J Wigglesworth1, David Sud, Tyler B Norsten
1Department of Chemistry, Simon Fraser University, Burnaby, BC, Canada.
Abstract:
A photoresponsive dithienylethene derivative bearing chiral pinene-based arms underwent a stereoselective photoinduced cyclization reaction to produce greater than 98% of a single diastereomer. The magnitude of the optical rotation changed as much as Delta[alpha]373 = 8698 degrees upon alternate irradiation with 400 nm and greater than 434 nm light.
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