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Deformability of multilamellar vesicles.

M Richterová¹, V Lisý

¹Department of Biophysics, Institute of Physics, P. J. Safárik University, Jesenná 5, 041 54 Kosice, Slovakia. richterova@upjs.sk

General Physiology and Biophysics

|May 19, 2005

Summary

Multilamellar vesicles exhibit effective surface tension due to bilayer interactions and bending rigidity. This study clarifies that bending rigidity (kappa) and droplet radius (R(0)) are key factors, not bilayer interactions.

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Area of Science:

Soft Matter Physics
Materials Science
Physical Chemistry

Background:

Unilamellar vesicles ideally have no surface tension.
Multilamellar vesicles, or "onions," display a measurable effective surface tension.
Existing models approximate this tension using bilayer interaction modulus (B), repeating distance (d0), and bending rigidity (kappa).

Purpose of the Study:

To calculate the contributions to the effective surface tension of a lamellar droplet.
To analyze cases with and without inter-bilayer interactions.
To refine understanding of factors governing multilamellar vesicle surface tension.

Main Methods:

Theoretical calculation of effective surface tension contributions.
Analysis of interacting and free vesicle layers.
Inclusion of non-zero layer surface tension for stressed membranes.

Main Results:

The contribution of inter-bilayer interactions to effective surface tension is minimal.
Effective surface tension is primarily determined by bending rigidity (kappa), droplet radius (R(0)), and the number of shape undulation modes (lmax).

Conclusions:

The effective surface tension of multilamellar vesicles is mainly governed by their bending rigidity and size.
Interactions between vesicle bilayers have a minor impact on the overall surface tension.
The model accounts for stressed vesicle membranes by including non-zero layer surface tension.

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