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Notch to remember

Rui M Costa1, Camilla Drew, Alcino J Silva

  • 1Departments of Neurobiology, Psychiatry, and Psychology, University of California-Los Angeles, 695 Young Drive South, Room 2554, Box 951761, Los Angeles, CA 90095-1761, USA.

Trends in Neurosciences
|June 1, 2005
PubMed

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The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Notch Signaling Pathway03:14

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The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule.
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
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