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Long-term outcomes in multiple gestations.

Larry Rand1, Keith A Eddleman, Joanne Stone

  • 1Maternal Fetal Medicine, Mount Sinai School of Medicine, 5 East 98th Street, Second floor, New York, NY 10029, USA. larry.rand@mssm.edu

Clinics in Perinatology
|June 1, 2005
PubMed
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Children from multiple pregnancies face higher risks of developmental issues like cerebral palsy and learning disabilities. Understanding these long-term outcomes is crucial for parents considering assisted reproductive technology (ART).

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Outcomes
  • Developmental Pediatrics

Background:

  • Multiple gestation pregnancies are increasing, partly due to assisted reproductive technology (ART).
  • Children born from multiple births have a higher risk of adverse neurodevelopmental outcomes.
  • These outcomes include cerebral palsy, learning disabilities, and language/neurobehavioral deficits.

Purpose of the Study:

  • To highlight the critical importance of long-term outcome counseling for parents.
  • To inform healthcare providers about the risks associated with multiple gestations.
  • To emphasize the need for knowledge regarding zygosity, gestational age, and multifetal pregnancy reduction.

Main Methods:

  • This abstract summarizes existing knowledge on the topic.

Related Experiment Videos

  • It emphasizes the importance of comprehensive counseling based on established risks.
  • No new experimental data were generated; it is a review of known outcomes.

    • Main Results:

    • Children from multiple gestations exhibit increased risks for significant developmental challenges.
    • These risks necessitate informed parental decision-making regarding conception and pregnancy management.
    • Factors like zygosity and gestational age influence the spectrum of potential deficits.

    Conclusions:

    • Parents facing multiple gestations or considering ART require thorough counseling on potential long-term neurodevelopmental risks.
    • Healthcare providers must be knowledgeable about these risks and management options.
    • Proactive counseling can support informed choices and better preparation for affected families.