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Updated: Aug 17, 2026

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
Published on: February 23, 2017
Preparation and characterization of a novel pH-sensitive ion exchange resin
Hongfei Liu1, Shu Zhang, Shufang Nie
1Department of Pharmaceutics, Shen yang Pharmaceutical University, Shen yang 110016, People's Republic of China. liuhongfei1979@sohu.com
Abstract:
Methylacrylic acid/styrene cross-linked with divinylbenzene is a novel pH-sensitive ion exchange resin. Microspheres of this resin were characterized by Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The microspheres showed a pulsatile swelling behavior when the pH of the media changed. The pH-sensitive microspheres were loaded with salbutamol sulfate and the drug-release characteristics were studied under both simulated gastric and intestinal pH conditions. The results obtained showed that the drug release also depended on the pH of the release media.
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