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[Biotransformation of mexidol in inbred BALB/C and C57BL/6 mice]
Eksperimental'Naia I Klinicheskaia Farmakologiia
|June 7, 2005
Abstract:
The pharmacokinetics and biotransformation of mexidol was studied in BALB/C and C57BL/6 mice. The blood plasma contains dealkylated metabolites, and the urine contains glucuronoconjugated derivatives of the drug. The process of glucuronoconjugation more intensively proceeds in C57BL/6 mice than in BALB/C mice.

