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Autoimmune hemolytic anemia due to monoclonal IgM lambda anti-Tja (Anti-P+1+Pk)
Y S Shechter1, H Rosenbaum, Y Scharf
1Blood Bank and Haematology Department, Rambam Medical Center; Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Abstract:
A patient with autoimmune hemolytic anemia of the cold antibody type is described. The monoclonal autoantibody had mu heavy and lambda light chains and Tja blood group specificity. The antibody resulted in acute hemolysis responsive to steroid treatment and appeared simultaneously with an increase in CMV titer.
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