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Angioedema acute hypersensitivity reaction to injectable hyaluronic acid
Janie M Leonhardt1, Naomi Lawrence, Rhoda S Narins
1Center for Dermatologic Surgery, Cooper University Hospital, Marlton, New Jersey 08053, USA.
Background:
Injectable hyaluronic acid was introduced to European markets in 1996 and has demonstrated a high safety profile. We describe the first reported case of angioedema-type hypersensitivity following injection of the upper lip with non-animal-stabilized hyaluronic acid (NASHA) gel.
Objective:
To report a case and discuss a potential mechanism for and treatment of angioedema-type hypersensitivity following injection with NASHA gel into the upper lip.
Methods And Materials:
Not applicable.
Results:
Not applicable.
Conclusion:
Although injectable hyaluronic acid has a high safety profile, this reaction is dramatic. Treatments and potential mechanisms are discussed.
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