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[Norwegian scabies: etiological grounds (author's transl)]
Annales De Dermatologie Et De Venereologie
|June 1, 1979
Summary
Norwegian scabies, a severe form of Sarcoptes scabiei infestation, presents with hyperkeratotic lesions. Altered host factors, like immunologic deficits, are key to its pathogenesis.
Area of Science:
- Dermatology
- Parasitology
- Immunology
Background:
- Norwegian scabies is a rare, hyperkeratotic variant of human scabies caused by Sarcoptes scabiei var. hominis.
- It is characterized by extensive skin lesions teeming with mites, often affecting the palms, soles, scalp, and ears.
Observation:
- The study details three cases of Norwegian scabies.
- Case 1: An elderly, debilitated woman with Recklinghausen's disease.
- Case 2: A boy with Down's syndrome.
- Case 3: A child undergoing immunosuppressive therapy.
Findings:
- The pathogenesis of Norwegian scabies remains unclear.
- Altered host factors are considered the principal determinant.
- These include specific immunologic deficits (primary or secondary) and an inability to eliminate mites due to lack of scratching.
- Hereditary predisposition to keratotic skin reactions may also play a role.
Implications:
- Understanding the role of host factors is crucial for managing Norwegian scabies.
- This condition highlights the importance of immune status and skin barrier function in parasitic infections.
- Further research into the specific immunologic and genetic factors is warranted.