[Distribution of periventricular necrosis and mild pathomorphologic changes in the brain in hypoxic-ischemic...

An analysis of histotopographic sections from 31 neonatal brains with hypoxic periventricular necroses. Distribution and topography of necroses was traced in 7 frontal planes in correlation to frequency of impaired white matter tracts. Results were summarized in schemes. Another topic of analysis was morphology of a slight white matter impairment (spongiosis). Used three grade classification of slight white matter impairment contributed to morphologic criteria of neonatal hypoxic-ischemic encephalopathy. Having considered his own findings and data from literature the author decided a standard histological tissue sampling for perinatal encephalopathies.