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Liuweidihuang-tang improves spatial memory function and increases neurogenesis in the dentate gyrus in rats
Kwang-Sik Lee1, Baek-Vin Lim, Hyun-Kyung Chang
1Kohwang Medical Research Institute, College of Medicine, Kyung Hee University, Seoul, South Korea.
Abstract:
The aqueous extract of Liuweidihuang-tang given to rats at doses of 100 mg/kg/day for 10 days induced a reduction in the frequency of error and increased neurogenesis in the hippocampal dentate gyrus. Our data suggest that Liuweidihuang-tang improves spatial learning ability by increasing neurogenesis in the dentate gyrus.
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