[Sterile eosinophilic pustulosis (Ofuji)--Mediterranean and endemic case]

Sterile eosinophilic pustulosis (Ofuji's disease) is very rare in Europe compared with Japan. We describe a Turkish and a German case. Clinical and histopathological findings do not allow a clearcut diagnosis. Many differential diagnoses have to be excluded, mainly by histopathological investigations. Careful examination of the heart and other internal organs is also necessary, since Ofuji's disease belongs to the group of hypereosinophilic diseases. Transitions from cutaneous to internal manifestations of hypereosinophilic disease may exist.