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PHYML Online--a web server for fast maximum likelihood-based phylogenetic inference.

Stéphane Guindon1, Franck Lethiec, Patrice Duroux

  • 1Bioinformatics Institute and Allan Wilson Centre, University of Auckland Private Bag 92019, Auckland, New Zealand.

Nucleic Acids Research
|June 28, 2005
PubMed
Summary
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PHYML Online offers a fast and accurate web tool for constructing phylogenetic trees from DNA and protein sequences. It supports comprehensive evolutionary analyses on large datasets efficiently.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Evolutionary Biology

Background:

  • Phylogenetic analysis is crucial for understanding evolutionary relationships.
  • Estimating evolutionary trees from sequence data can be computationally intensive.
  • Existing methods may lack speed or comprehensive features for large datasets.

Purpose of the Study:

  • To present PHYML Online, a web interface for the PHYML software.
  • To provide a fast and accurate tool for maximum likelihood phylogenetic inference.
  • To enable comprehensive phylogenetic analyses on large biological datasets.

Main Methods:

  • Utilizes the PHYML algorithm, a fast and accurate heuristic for phylogenetic tree estimation.
  • Web interface allows users to input DNA and protein sequences.

Related Experiment Videos

  • Offers options for nonparametric bootstrap and estimation of evolutionary parameters.

    • Main Results:

    • PHYML Online facilitates efficient phylogenetic analyses of large sequence datasets.
    • The tool provides a user-friendly platform for maximum likelihood-based tree inference.
    • Supports various options for robust phylogenetic analysis and parameter estimation.

    Conclusions:

    • PHYML Online is a valuable resource for researchers requiring efficient and accurate phylogenetic analyses.
    • The web server enhances accessibility to advanced phylogenetic inference methods.
    • Enables comprehensive evolutionary studies on large-scale biological data.