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Updated: Aug 9, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
Multiple myeloma with scleroderma-like changes
C Paredes-Suárez1, V Fernández-Redondo, M Vázquez Blanco
1Department of Dermatology, Complejo Hospitalario Universitario, Faculty of Medicine, 15782 Santiago de Compostela, Spain. mejaime@usc.es
Abstract:
We present a case of a patient who presented concomitantly with generalized pruritus, brownish sclerodermatous plaques, sclerodactyly and a monoclonal band for IgG-kappa. The patient was diagnosed as having multiple myeloma by bone marrow examination. The rapidly progressive evolution with acute anuric renal failure, malignant hypertension and the skin sclerosis seem to be related to the neoplastic disorder. The scleroderma-like changes have to be differentiated from systemic scleroderma.
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