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Updated: Aug 2, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Inverted nasosinusal papilloma. 11 cases and bibliographic revision]
D Alonso Párraga1, A Clemente García, D Sánchez Ruiz
1Sección Rinológía, Servicio ORL, Complejo H. Universitario Xeral-Cíes.
Introduction:
We present the cases registred from 1998 to 2003 and a revision of the bibliography.
Material And Method:
In the section of Rhinology of a second level Hospital 11 patients affected by inverted papilloma type 1 of the OMS classification were diagnosed aged between 40 and 79, 9 men and 2 women. They were explored through endoscopy and biopsy and the exeresis of the lesion was done by endoscopic polipectomy with microdebrider (PEM).
Results:
All the cases at stage I, II and III of the Krouse classification. Treated by CEN, 6 by mixed endonasal approach and through the canine fossa 4 by nasal approach only and 1 by Caldwell-Luc approach. The follow-up was done between 9 to 64 months and there was a recidive who was operated by open surgery and no one malignant transformation was seen.
Discussion:
We coment the aspects related to etiology, the symptons and the surgical technics.
Conclusions:
We propose to stage the tumor and the realisation of a PEM with topic anesthesia with deep biopsies in all unilateral poly formations to avoid a retarded diagnosis and to be able to apply endoscopic technics.
